Correction: Comparative Genomic Analysis Reveals 2-Oxoacid Dehydrogenase Complex Lipoylation Correlation with Aerobiosis in Archaea
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Copyright: 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Figure 2. Phylogenetic analysis of LipM and LplA. Maximum likelihood phylogenetic tree including 131 LipM and LplA sequences from archaea, LplA sequences from major eukaryotic species (S. cerevisiae, D. melanogaster, M. musculus and H. sapiens) and LplA and LipM sequences from eubacteria representing Actinobacteria (S. coelicolor), Bacteroidetes (B. thetaiotaomicron), Firmicutes (B. subtilis and S. aureus) and Proteobacteria (E. coli andB. pseudomallei). Putative cases of horizontal gene transfer are indicated (asterisk) and major phylogenetic clades are highlighted: archaeal LplA (Clade I orange; Clade II green), LipM (red), and eukaryotic and eubacterial LplA (blue). The full phylogenetic tree including species names and bootstrap values is provided Figure S2. doi:10.1371/journal.pone.0087063.g002
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Comparative Genomic Analysis Reveals 2-Oxoacid Dehydrogenase Complex Lipoylation Correlation with Aerobiosis in Archaea
Metagenomic analyses have advanced our understanding of ecological microbial diversity, but to what extent can metagenomic data be used to predict the metabolic capacity of difficult-to-study organisms and their abiotic environmental interactions? We tackle this question, using a comparative genomic approach, by considering the molecular basis of aerobiosis within archaea. Lipoylation, the cova...
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